Historical Uses
- Traditional Chinese Medicine (TCM): Astragalus has been used for thousands of years, primarily as a tonic herb to boost energy (qi) and immune strength, increase vitality, and protect against disease.
- Traditional Uses: Often used to treat fatigue, respiratory infections, and other conditions where the body needs support in recovering strength and resilience.
Modern Clinical Uses by Herbalists & Naturopaths
- Immune Support: Commonly used to enhance immune function and reduce the frequency of colds, flu, and respiratory infections.
- Adaptogen: Considered an adaptogenic herb, it is believed to help the body cope with physical and mental stress.
- Heart Health: Used for its purported benefits in supporting cardiovascular health, improving circulation, and managing cholesterol.
- Chronic Fatigue and Energy: Recommended by naturopaths for boosting energy in cases of chronic fatigue and debility.
Chemistry
- Key Compounds: Astragalus contains polysaccharides, flavonoids, saponins (astragalosides), and amino acids.
- Astragalosides: Astragaloside IV is one of the main active components with potential benefits in immune modulation, anti-inflammatory, and anti-aging effects.
- Polysaccharides: These contribute to its immune-modulating properties.
Pharmacology
- Immune Modulation: Astragalus is believed to stimulate immune cells, including macrophages and T-cells.
- Antioxidant Properties: It has been shown to reduce oxidative stress, which may protect cells and support longevity.
- Anti-Inflammatory Actions: Astragalus extracts may help reduce inflammatory responses, supporting recovery from illness and injury.
- Telomerase Activation: Some studies suggest that Astragalus may stimulate telomerase, an enzyme linked to cell longevity.
Summary of Clinical Trials
- Immune Support: Several clinical trials support Astragalus’ role in enhancing immune response, showing reduced frequency and severity of colds and respiratory infections.
- Cardiovascular Health: Some clinical trials show positive effects on cardiac function, particularly in chronic heart failure patients, where Astragalus has improved heart performance and reduced symptoms.
- Kidney Health: Clinical studies have explored its potential benefits in chronic kidney disease, where it may help reduce proteinuria and improve renal function.
- Anti-Aging and Telomerase: Some studies, though still in early stages, support its potential for longevity by stimulating telomerase activity.
In summary, Astragalus is widely used in both traditional and modern natural medicine for immune enhancement, stress adaptation, cardiovascular support, and anti-aging effects. Its safety profile is favorable when used correctly, though further high-quality studies could strengthen clinical evidence for its efficacy.
Generated by ChatGPT; edited by Dr. Christopher Hobbs