Condition
Treatment Support
infection fighter
Application
tincture, tea
Boneset
(Eupatorium perfoliatum)
Also know as Thoroughwort
Botanical Information
A perennial herb of moist, rich soil of the eastern U.S. with opposite leaves that clasp the main stem and numerous white flowers.
Working with Boneset
Part(s) Used
Leaf, Flowers
Herb Forms
Tinctures, capsules, bulk herb, powder
Christopher Hobbs:
“Boneset is used for various respiratory ailments, such as asthma, bronchitis, unproductive coughs, and pneumonia. It is called for in flu (specifically with deep aching) and fever, as well as for chicken pox and broken bones. Boneset is said to increase the body’s resistance to infection and may have an antiviral effect.
Boneset has a taste of BITTER, ACRID and a temperature of COOL.”
Boneset is a perennial plant historically used by Native Americans and early settlers for its medicinal benefits, especially for treating fevers, colds, and respiratory infections. The plant is native to North America, often found in wetlands and meadows. Here’s a brief overview of its various aspects:
Historical Uses
Boneset has been traditionally used to treat influenza, fever, aches, and colds. The name “boneset” originates from its use in treating “breakbone fever” (dengue fever), as it was believed to alleviate the severe body pain associated with the illness. Native Americans used boneset as a remedy for various ailments, including respiratory infections, digestive issues, and arthritis.
Modern Clinical Uses by Herbalists and Naturopaths
Today, herbalists and naturopaths use boneset primarily to support the immune system and relieve symptoms of flu, colds, and other upper respiratory tract infections. It is thought to act as an immune stimulant and to reduce fever by promoting sweating. Boneset is also used for mild digestive issues due to its purported anti-inflammatory and anti-microbial properties.
Chemistry
Boneset contains a variety of bioactive compounds, including:
- Sesquiterpene lactones (e.g., eupafolin and euparin), thought to be responsible for its anti-inflammatory and immune-modulating effects.
- Flavonoids (e.g., quercetin and kaempferol) with antioxidant properties.
- Polysaccharides, which may support immune function.
Pharmacology
The sesquiterpene lactones are believed to inhibit inflammatory pathways and modulate immune responses, while flavonoids offer antioxidant protection. Studies suggest these compounds may also have mild antimicrobial effects, which could contribute to boneset’s historical use in treating infections.
Summary of Clinical Trials
There are limited clinical trials on boneset. Some studies have investigated its immune-supportive properties and fever-reducing effects, but the data are largely preliminary. Most evidence remains anecdotal or based on traditional use, and more rigorous clinical trials are needed to confirm efficacy and safety.
Conclusion
Boneset has a rich history in traditional medicine, particularly for treating flu-like symptoms. While modern herbalists use it for similar purposes, its clinical efficacy remains under-researched. Safety concerns over liver toxicity warrant careful use, especially in high doses or over long periods.
Generated by ChatGPT; edited by Christopher Hobbs.
Cautions
Boneset should be used cautiously, as it contains pyrrolizidine alkaloids (PAs), which, if consumed in high doses or over prolonged periods, may cause liver toxicity. Short-term, moderate use appears safe for most people, but boneset is generally not recommended for pregnant or breastfeeding women, children, or individuals with liver disease. Side effects can include nausea and vomiting, especially at high doses.
Not for long-term use (longer than two weeks). Avoid use altogether if you have preexisting liver problems like hepatitis; contains small amounts of chemical compounds that stress the liver. Care should be taken with dosing, as excessive amounts may lead to adverse effects.
Conditions treated with Boneset
Condition
Treatment Support
Application
Condition
Treatment Support
anti-infection
Application
tincture, tea, capsule
The information given here is designed to help you make informed choices about your health. The information is drawn from numerous sources—both traditional medicine practice, from the clinical experience of many herbalists currently practicing, and supported by decades of scientific research from the author. The research most consulted includes human clinical trials that help to determine the most effective and safe herbs for various needs, the best doses, and types of preparations.
The information offered in this database is not intended as a substitute for any that may have been prescribed by your health practitioner or physician.
