Cascara Sagrada

Christopher Hobbs:

“Cascara sagrada is an excellent laxative, which moistens and helps re-educate bowels that are atonic and not working properly. It is also used for hemorrhoids and jaundice, and it increases the liver’s ability to produce bile. Its bitter and slightly sweet nature makes cascara a stimulating tonic. Another side of cascara is its bitter and cool nature which is useful for relieving “damp heat,” a condition that predisposes to infections of the abdominal and pelvic area like bladder infections, bowel infections, and vaginal infections. Cascara tea may be applied as a wash for lice or scabies.
The indicated dose is for mild cases of constipation or other conditions. For stubborn cases, use the indicated dose morning and evening.

Cascara Sagrada has a taste of BITTER and a temperature of COLD.”

Cascara Sagrada (Rhamnus purshiana), commonly known as “sacred bark,” has a long history in traditional medicine and is primarily valued as a natural laxative. Here’s a summary of its historical uses, modern applications, chemistry, pharmacology, safety, dosages, and current clinical insights:

Historical Uses

Native Americans traditionally used Cascara Sagrada for its laxative effects, as well as for digestive health. European settlers later adopted it, and it became a popular over-the-counter remedy in the 19th century.

Modern Clinical Uses

Today, herbalists and naturopaths still use cascara sagrada primarily for constipation relief. It is also used occasionally in formulas targeting digestive health and liver function, though this is less common and supported by limited evidence.

Chemistry and Pharmacology

The main active compounds in cascara sagrada are anthraquinone derivatives, particularly cascarosides. These compounds stimulate the colon, promoting bowel movements. When dried, the bark’s purgative effects become less harsh, which is why it’s typically aged before use to reduce potential side effects.

Clinical Trials

Few clinical trials have thoroughly studied cascara sagrada. Existing studies primarily support its efficacy as a short-term laxative but highlight a need for caution with prolonged use. Evidence on other purported benefits remains inconclusive, with ongoing research needed to clarify its long-term safety and broader effects.

Summary

Cascara sagrada remains a useful, short-term herbal remedy for constipation, especially when other treatments are insufficient. Its efficacy and safety, however, are primarily backed by tradition and some limited pharmacological evidence, suggesting more robust clinical research would be beneficial.

Generated by ChatGPT; edited by Christopher Hobbs.