Cat’s Claw

Christopher Hobbs:

“Cat’s claw is a widespread vine growing in the Amazon. There is little traditional use information available–it was apparently not widely used by native peoples, except in a very small area of Peru. Austrian researchers became interested in the herb in the late 1970s when they heard a report that it miraculously cured a case of advanced cancer. A number of constituents have been isolated and identified, but little pharmacological or clinical research has been performed on the herb. Preliminary scientific studies have shown it to have immune-stimulating and anti-inflammatory properties. Cat’s claw is being touted by some companies in the U.S. herb industry as a “cure-all,” similar to the South American herbs Suma (Pfaffia paniculata) and Pau d’arco (Tabebuia spp.). The herb may be effective for some ailments, but it needs more research before a definitive statement about its exact applications and contraindications can be made.
It is currently being touted as a benefit to HIV patients by some herbal practitioners who have used it. It is also being used as an aid to help relieve the symptoms of dermatological disorders (dermatitis, acne), allergies, arthritis, inflammatory bowel syndromes (irritable bowel syndrome), herpes, and most of all cancer.

Cat’s claw has a taste of and a temperature of COOL.”

Historical Uses: Cat’s claw (Uncaria tomentosa and Uncaria guianensis) is a vine native to the Amazon rainforest and other tropical areas of Central and South America. Indigenous tribes have traditionally used it for over 2,000 years as a treatment for inflammation, infections, arthritis, digestive disorders, and to boost the immune system. Its name comes from the hook-like thorns resembling a cat’s claw.

Modern Clinical Uses: Today, cat’s claw is utilized by herbalists and naturopaths mainly for its anti-inflammatory and immune-boosting properties. It is often prescribed as a supplement for arthritis, joint pain, viral infections, digestive issues, and to enhance immune function.

Chemistry: The primary active compounds in cat’s claw are alkaloids (such as pentacyclic oxindole alkaloids), glycosides, tannins, and flavonoids. These compounds are believed to interact with the immune system, reduce inflammation, and provide antioxidant protection.

Pharmacology: Research has demonstrated that pentacyclic oxindole alkaloids, in particular, may modulate the immune response, increase white blood cell counts, and potentially support anti-inflammatory and antiviral activities. The presence of other compounds like quinovic acid glycosides also shows anti-inflammatory and analgesic properties.

Clinical Trials: Preliminary studies have shown some promise in using cat’s claw for osteoarthritis and rheumatoid arthritis, with improvements in pain and joint function. Other trials have investigated its potential in treating viral infections, but large-scale human studies are limited, so its effectiveness for these uses is not fully validated.

Summary

Cat’s claw shows potential benefits for inflammatory and immune-related conditions, with a long history of traditional use. While it is generally safe, more clinical research is needed to confirm its efficacy and clarify safe usage parameters.

Generated by ChatGPT; edited by Christopher Hobbs.