Celery

Historical Uses
Celery (Apium graveolens) has been used since ancient times in traditional medicine across many cultures, particularly in Egypt, Greece, and China. Historically, celery was valued for its diuretic, anti-inflammatory, and digestive properties. It was used to treat ailments like high blood pressure, joint pain, and poor digestion.

Modern Clinical Uses
Today, herbalists and naturopaths use celery seed extracts primarily for managing hypertension, gout, arthritis, and digestive issues. It’s also used for its antioxidant and anti-inflammatory effects, which may help support joint health, reduce bloating, and improve cardiovascular health. Celery seed extract is a popular supplement, especially in natural and integrative medicine. Celery juice and whole celery are often consumed as part of a balanced diet.

Chemistry
Celery contains several active compounds, including flavonoids (like apigenin and luteolin), volatile oils (notably limonene, selinene, and myrcene), and phthalides (3-n-butylphthalide). These compounds are thought to contribute to its therapeutic effects, particularly its anti-inflammatory, antioxidant, and antihypertensive properties.

Pharmacology
Research suggests that celery’s active compounds may exert a range of effects:

• Antioxidant activity: Helps neutralize free radicals and reduce oxidative stress.
• Anti-inflammatory effects: May inhibit inflammatory enzymes, potentially aiding in conditions like arthritis.
• Antihypertensive effects: Phthalides are believed to relax blood vessel walls, which may lower blood pressure.