Perilla

Christopher Hobbs:

“Perilla is useful during pregnancy to alleviate nausea and for calming a restless fetus. It is also used for general stomach disorders, such as lack of appetite, vomiting, or nausea. In Chinese medicine, perilla is used in decoctions to alleviate the symptoms of colds, such as chills, nasal congestion, and coughs, especially when the cold is due to exposure to damp and cold.

Perilla has a taste of ACRID, AROMATIC and a temperature of WARM.”

In modern herbalism and naturopathy, perilla is used for a range of health concerns, including:

• Respiratory health: To ease symptoms of asthma, allergies, and bronchitis.
• Anti-inflammatory: Used for conditions like arthritis and skin conditions due to its anti-inflammatory properties.
• Antioxidant and anti-cancer: Rich in polyphenols, including rosmarinic acid, which is believed to have antioxidant effects.
• Digestive health: Traditionally used to treat nausea and improve appetite.

Chemistry and Pharmacology

Perilla contains a variety of bioactive compounds:

• Flavonoids: Apigenin and luteolin, known for their anti-inflammatory and antioxidant effects.
• Phenolic compounds: Like rosmarinic acid, which have been shown to have anti-inflammatory and immune-boosting properties.
• Omega-3 fatty acids: Especially alpha-linolenic acid (ALA), beneficial for heart health and inflammation.

Pharmacologically, perilla’s compounds affect several pathways:

• Anti-inflammatory: Inhibition of cyclooxygenase (COX) enzymes.
• Antioxidant: Scavenging free radicals and protecting cells from oxidative damage.
• Immunomodulation: Boosting or balancing the immune system.

Dosages:

Typical dosages vary depending on the form (e.g., leaf, seed oil, extract):

• Perilla leaf: 1-2 grams of dried leaf per day.
• Perilla seed oil: 1-3 teaspoons (5-15 mL) daily.
• Extracts: Dosages can range from 200-500 mg per day, depending on the concentration.

Always consult a healthcare professional before use, especially for specific medical conditions.

Summary of Clinical Trials

Clinical trials on perilla are limited but promising in several areas:

• Asthma and Allergies: Some studies suggest that perilla leaf extract may help reduce symptoms of asthma and allergic rhinitis by acting as a bronchodilator and anti-inflammatory.
• Inflammation: Clinical studies indicate that perilla oil has a positive effect on inflammatory markers, potentially benefiting conditions like arthritis.
• Cognitive function and mood: Some research points to its potential for improving cognitive function and reducing anxiety, though more evidence is needed.

In conclusion, perilla shows potential in several therapeutic areas, but further large-scale clinical trials are necessary to confirm its efficacy and safety.

Generated by ChatGPT; edited by Christopher Hobbs