Condition
Treatment Support
anti-addictive, nervine
Application
tincture, capsules
Skullcap
(Scutellaria lateriflora)
Botanical Information
A slender perennial from the Mint family with opposite leaves and 2-lipped blue flowers attached to the leaf nodes, with both pairs on pointing out from the same side of the stem, because one pair is bent back to align with the other pair.
Working with Skullcap
Part(s) Used
Leaf, Flowers
Herb Forms
Tincture, capsule, bulk herb, powder
Christopher Hobbs:
“Herbalists widely recommend skullcap as a nervine, indicating broadly an herb that is tonifying to the nervous system. Skullcap is used to reduce nervousness and anxiety and, in some cases to treat insomnia, and modern studies have confirmed these uses. It is mild and not a true sedative, but if taken for some weeks, it can reliably help calm jittery nerves and works well with a stronger herb like valerian. Skullcap’s action complements other nervines, and it is useful in a larger group, such as with hops, passionflower, and lavender.
Skullcap is also used for spasms, neuralgia, and epilepsy. In earlier times, the herb was often prescribed as a cure for rabies and the bites of mad dogs. Other older uses in folk medicine include treating excessive sexual desire (though there is no modern evidence to support this use) and to relieve addictions.
Its Chinese counterpart, Scutellaria baicalensis, is used to remove heat from the respiratory and digestive systems and to lower blood pressure.
Skullcap has a taste of BITTER, SWEET and a temperature of COOL.”
Historical Uses
Skullcap has been used in traditional medicine for centuries.
Western Herbalism: Scutellaria lateriflora (American skullcap) was historically used as a nervine to treat anxiety, insomnia, and seizures.
Modern Clinical Uses by Herbalists and Naturopaths
- Nervous System Support: To alleviate anxiety, stress, and insomnia.
- Anti-inflammatory and Antioxidant: Used for conditions such as arthritis and chronic inflammation.
- Immune Support: For upper respiratory infections and immune modulation.
- Liver Protection: Â To protect and detoxify the liver.
Chemistry
- American skullcap has unique compounds like scutellarin, which contributes to its nervine effects.
- Rich in polyphenols, alkaloids, and essential oils.
Pharmacology
- CNS Effects: Baicalin and scutellarin modulate GABA receptors, promoting calmness and neuroprotection.
- Anti-inflammatory Activity: Inhibits COX-2 and NF-κB pathways.
- Antiviral: Active against certain viruses by inhibiting replication.
- Antioxidant: Neutralizes free radicals and reduces oxidative stress.
Clinical Trials
- Preliminary trials suggest American skullcap has anxiolytic and sedative effects.
- Limited large-scale human trials exist, though research supports its traditional uses.
Summary
Skullcap is a versatile herb with historical roots and modern applications, particularly in nervous system support and inflammation management. While its safety and efficacy are supported by preclinical research and smaller trials, more rigorous human studies are needed. Always consult a professional before use.
Generated by ChatGPT; edited by Christopher Hobbs
Cautions
Generally safe when used at recommended doses.
Potential side effects include mild gastrointestinal discomfort or allergic reactions.
May interact with sedatives, anticoagulants, or hepatotoxic drugs.
High doses of skullcap historically raised concerns about hepatotoxicity, though more recent studies have largely dispelled this for uncontaminated sources.
A note of caution though: In commercial preparations, skullcap is sometimes adulterated, or the herb germander from the genus Teucrium is substituted for it. Germander is stressful on the livers of sensitive individuals and is best avoided. To ensure that you have the correct herb, which is entirely safe, it is recommended growing your own.
Conditions treated with Skullcap
Condition
Treatment Support
Application
Condition
Treatment Support
nervine
Application
tincture, tablet, capsule, tea
Condition
Treatment Support
antispasmodic
Application
tincture, tablet, capsule, tea
Condition
Treatment Support
strengthening nervine, bitter digestive tonic
Application
tincture, tea
Condition
Treatment Support
nervine
Application
tea, tincture, capsule
Condition
Treatment Support
anaphrodisiac
Application
tincture, tea, capsule
The information given here is designed to help you make informed choices about your health. The information is drawn from numerous sources—both traditional medicine practice, from the clinical experience of many herbalists currently practicing, and supported by decades of scientific research from the author. The research most consulted includes human clinical trials that help to determine the most effective and safe herbs for various needs, the best doses, and types of preparations.
The information offered in this database is not intended as a substitute for any that may have been prescribed by your health practitioner or physician.
